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Central Nervous system Part 1 Discussion

Central Nervous system Part 1 Discussion

Q 1. Why are ions and glucose necessary components of the cerebral spinal fluid? 2. Explain what adaptations make the blood brain barrier relatively impermeable. 3. Vistaril is an anti-histamine that is able to pass through the blood brain barrier. However, Allegra is an anti-histamine that is not able to pass through the blood brain barrier. Using your knowledge of the blood brain barrier explain, why only vistaril is permeable.

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1. Glucose is necessary components because neurons synthesizes ATP using glucose via reactions dependent on oxygen . Glucose is not stored in the brain , it is required for the constant supply from the blood . Glucose is transported by the process of active transport mechanism and it is the primary energy substrate for the brain and the glucose transport protein is highly enriched in brain capillary endothelial cells. Ions such as potassium and sodium are required for the normal functioning of the nervous system and the transport of impulses .